Detecting Local Haplotype Sharing and Haplotype Association
نویسندگان
چکیده
منابع مشابه
Detecting Local Haplotype Sharing and Haplotype Association
A novel haplotype association method is presented, and its power is demonstrated. Relying on a statistical model for linkage disequilibrium (LD), the method first infers ancestral haplotypes and their loadings at each marker for each individual. The loadings are then used to quantify local haplotype sharing between individuals at each marker. A statistical model was developed to link the local ...
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ژورنال
عنوان ژورنال: Genetics
سال: 2014
ISSN: 1943-2631
DOI: 10.1534/genetics.114.164814